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Saturday, December 8, 2012

Charcot–Marie–Tooth disease

Charcot–Marie–Tooth disease (CMT) , also known as Charcot–Marie–Tooth
neuropathy , hereditarymotor and sensory neuropathy (HMSN) and
peroneal muscular atrophy (PMA) — is a genetically and clinically
heterogeneous group of inherited disorders of the peripheral nervous
system characterised by progressive loss ofmuscle tissue and touch
sensation across various parts of the body. Currently incurable, this
disease is one of the most common inherited neurological disorders
affecting approximately 1 in 2,500 people equating to approximately
23,000 people in the United Kingdom and 125,000 people in the USA .
CMT was previously classified as a subtype of muscular dystrophy

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